How Does High Dose Intravenous Vitamin C Kill Cancer?

Watch this video to understand how high dose intravenous vitamin C kills cancer cells.

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FACT! High dose vitamin C kills cancer cells. This is confirmed by research carried out by top Doctors from the National Cancer Institute, Harvard Medical School, Sloan Kettering, MD Anderson, and many others. I can’t wait to review the evidence, but most importantly by the end of this video you will understand how high dose intravenous vitamin C actually kills cancer cells.

Recent research reveals how high dose vitamin C kills cancer cells.

High dose intravenous vitamin C (also called IVC), has been used by Integrative Oncology practitioners for over 50 years, but the mechanisms of action (how it works) have been a mystery for most of that period. Breakthrough research over the last several years has helped clarify how IVC actually kills cancer cells. 

Here are a few examples:

Dr. Mark Levine, National Institute of Health

As early as 2008 Mark Levine’s team at NIH were observing in tests that high doses of vitamin C were killing cancer cells by applying oxidative stress. They noted that cancer cells often lack something called “catalase” which made them susceptible to the IVC. These discoveries paved the way for others.

Dr. Jihye Yun and Dr. Lewis Cantley study shows high dose vitamin C kills cancer using oxidative stress.

Dr. Jihye Yun, MD Anderson

Dr. Lewis Cantley, Cornell Cancer Center

In November of 2015 Dr. Jihye Yun of MD Anderson (the #1 ranked cancer hospital) documented that high levels of vitamin C selectively caused oxidative stress on cancer cells leading to cell death. Dr. Lewis Cantley was a member of this research team. At that time he was the Director of the Cornell Cancer Center, using this evidence he secured funding to launch a Phase 2 trial using IVC for colorectal, pancreatic, and lung cancer.

Dr. Schoenfeld lead a study that shows IVC damages cancer cells with oxidative stress.

Dr. Joshua Schoenfeld, Sloan Kettering

In March of 2017, Sloan Kettering’s Dr. Joshua Schoenfeld completed a study at the University of Iowa where he demonstrated that IVC damaged and killed cancer cells via oxidative stress.

Dr. Joseph Cullen, Holden Comprehensive Cancer Center

Dr. Joseph Cullen of the National Cancer Institute designated Holden Comprehensive Center leads the world in studying IVC in a clinical setting. Between 2010 to May 2023 he has co-authored 41 publications on using high dose vitamin C to treat cancer, many of which describe oxidative stress as the mechanism of action that brings about cancer cell death.

IVC multi-targeting agent against cancer

While studies suggest IVC has the capacity to be a multi-targeting agent that can destroy cancer cells in 13 different ways, my quick review of several studies helped emphasize that oxidative stress is the number one observed mechanism of action for IVC.

How does high dose intravenous vitamin C kill cancer cells using oxidative stress?

Well, most people think of vitamin C as an antioxidant that protects cells in the body from free radicals. However, the research proves that when high doses of vitamin C are given intravenously, the vitamin C becomes a pro-oxidant when it comes into contact with cancer cells. By the way, a pro-oxidant is a substance that causes damage to cell membranes, proteins and even DNA; this damage can lead to cell death.

IVC generates a tremendous amount of pro-oxidants around and inside cancer cells because generally cancer likes to maintain high levels of iron around and inside of their cell. When this iron comes into contact with high and steady levels of vitamin C, it triggers something called the Fenton Reaction.

This Fenton Reaction continuously occurs while vitamin C levels are high, which results in continuously generating the pro-oxidants Hydrogen peroxide and hydroxyl radicals. These two are very harmful to cancer cells and form an attack against the outside of the cell, that oftentimes transitions to inside of the cancer cell where DNA, proteins, and lipids get damaged leading to cancer cell death.

Another factor of the Fenton Reaction is that vitamin C is converted into DHA (dehydroascorbic acid). The DHA structure so happens to look a lot like sugar. So much so, that it can trick glucose hungry cancer cells into consuming the DHA. But upon intaking the DHA, cancer cells are not happy with it. So they will spend a lot of effort to reduce it back out, this depletes critical substances like glutathione and NAD in the cancer cell which triggers an energy crisis leading to cell death.

The evidence shows these described mechanisms of action are what make IVC potent as an anti-cancer treatment, particularly when combined with chemotherapy, radiation, and immunotherapies.

For those interested in pursuing this treatment, you can schedule a no cost consultation by selecting the link to the Personalized Medicine website in the video description.

Medical Advice Disclaimer:
The information, including but not limited to, text, graphics, images and other material contained on this website are for information purposes only and was based on the latest research accessible to the author at the time of publication. No material on this site is intended to be a substitute for professional medical advice, diagnosis or treatment. Always seek the advice of your physician or other qualified health care provider with any questions you may have regarding a medical condition or treatment and before undertaking a new healthcare regiment, and never disregard professional medical advice or delay in seeking it because of something you have read on this website.

View other articles about the high dose vitamin C cancer treatment:

Olena Ivanova, MS, FNP-C

Olena has over 10 years of clinical experience including work with Johns Hopkins Hospitals and University of Maryland Medical Center. She supported treating advanced cancer patients with sophisticated therapies that include stem cell transplants and cellular immunotherapy. She also has clinical experience diagnosing and treating patients with a variety of illness and chronic diseases.

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